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1

Beyond classical derivatization: analyte ‘derivatives’ in the bioanalysis of endogenous and exogenous compounds

Barnaby, Omar S, Benitex, Yulia, Cantone, Joseph L, McNaney, Colleen A, Olah, Timothy V, Drexler, Dieter M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

2

Application of ion trap technology to liquid chromatography/mass spectrometry quantitation of large peptides

Petia Shipkova, Dieter M. Drexler, Robert Langish, James Smalley, Mary Ellen Salyan, Mark Sanders

Journal:

Rapid Communications in Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 137 KB

english, 2008

3

Terahertz split-ring metamaterials as transducers for chemical sensors based on conducting polymers: a feasibility study with sensing of acidic and basic gases using polyaniline chemosensitive layer

Drexler, Christoph, Shishkanova, Tatiana V., Lange, Christoph, Danilov, Sergey N., Weiss, Dieter, Ganichev, Sergey D., Mirsky, Vladimir M.

Journal:

Microchimica Acta

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

4

Qualitative and quantitative characterization of the amyloid β peptide (Aβ) population in biological matrices using an immunoprecipitation–LC/MS assay

Michael J. Ford, Joseph L. Cantone, Craig Polson, Jeremy H. Toyn, Jere E. Meredith, Dieter M. Drexler

Journal:

Journal of Neuroscience Methods

Year:

2008

Language:

english

File:

PDF, 1.27 MB

english, 2008

5

Application of Cassette Ultracentrifugation Using Non-labeled Compounds and Liquid Chromatography-Tandem Mass Spectrometry Analysis for High-Throughput Protein Binding Determination

Kieltyka, Kasia, McAuliffe, Brian, Cianci, Christopher, Drexler, Dieter M., Shou, Wilson, Zhang, Jun

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 885 KB

english, 2016

6

Modified vaccinia virus Ankara delivers a robust surrogate marker for immune monitoring to sarcoma cells even if cells are being exposed to chemotherapy and heat treatment

Tschoep-Lechner, Katharina, Drexler, Ingo, Hammer, Doreen, Neumann, Daniel, Pohla, Heike, Sutter, Gerd, Noessner, Elfriede, Issels, Rolf-Dieter

Journal:

International Journal of Hyperthermia

Year:

2012

Language:

english

File:

PDF, 835 KB

english, 2012

7

Nocathiacins (I), New Thiazolyl Peptide Antibiotics from Nocardia sp. Part 2. Isolation, Characterization, and Structure Determination.

John E. Leet, Wenying Li, Helen A. Ax, James A. Matson, Stella Huang, Ron Huang, Joseph L. Cantone, Dieter Drexler, Richard A. Dalterio, Kin S. Lam

Journal:

Year:

2003

File:

PDF, 85 KB

2003

8

THREE-DIMENSIONAL ANALYSIS OF RETINAL MICROANEURYSMS WITH ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY

Karst, Sonja G., Salas, Matthias, Hafner, Julia, Scholda, Christoph, Vogl, Wolf-Dieter, Drexler, Wolfgang, Pircher, Michael, Schmidt-Erfurth, Ursula

Journal:

Year:

2018

Language:

english

File:

PDF, 818 KB

english, 2018

9

Utility of high-resolution accurate MS to eliminate interferences in the bioanalysis of ribavirin and its phosphate metabolites

Wei, Cong, Grace, James E, Zvyaga, Tatyana A, Drexler, Dieter M

Journal:

Year:

2012

Language:

english

File:

PDF, 751 KB

english, 2012

10

Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems

Kugler, Franziska, Drexler, Ingo, Protzer, Ulrike, Hoffmann, Dieter, Moeini, Hassan

Journal:

Virology Journal

Year:

2019

Language:

english

File:

PDF, 3.83 MB

english, 2019

11

Transcatheter Closure of Patent Foramen Ovale in Patients with Paradoxical Embolism. Procedural and Follow-up Results after Implantation of the Starflex® Occluder Device with Conjunctive Intensified Anticoagulation Regimen

DIETER FISCHER, MARTIN FUCHS, ARND SCHAEFER, BERNHARD SCHIEFFER, SMITA JATEGAONKAR, BURKHARD HORNIG, HELMUT DREXLER, GERD P. MEYER

Journal:

Journal of Interventional Cardiology

Year:

2008

Language:

english

File:

PDF, 946 KB

english, 2008

12

Utility of quantitative whole-body autoradiography (QWBA) and imaging mass spectrometry (IMS) by matrix-assisted laser desorption/ionization (MALDI) in the assessment of ocular distribution of drugs

Dieter M. Drexler, Sarah H. Tannehill-Gregg, Lifei Wang, Barry J. Brock

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 464 KB

english, 2011

13

Bioanalysis of acetylcarnitine in cerebrospinal fluid by HILIC-mass spectrometry

Holder, Brian R., McNaney, Colleen A., Luchetti, David, Schaeffer, Eric, Drexler, Dieter M.

Journal:

Biomedical Chromatography

Year:

2015

Language:

english

File:

PDF, 833 KB

english, 2015

14

Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat

Hiller, Thomas, Rasche, Andrea, Brändel, Stefan Dominik, König, Alexander, Jeworowski, Lara, Teague O’Mara, M., Cottontail, Veronika, Page, Rachel A., Glebe, Dieter, Drexler, Jan Felix, Tschapka, Marc

Journal:

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

15

Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues

Dieter M. Drexler, Timothy J. Garrett, Joseph L. Cantone, Richard W. Diters, James G. Mitroka, Maria C. Prieto Conaway, Stephen P. Adams, Richard A. Yost, Mark Sanders

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2007

Language:

english

File:

PDF, 604 KB

english, 2007

16

Analysis of Large Peptides by MALDI Using a Linear Quadrupole Ion Trap with Mass Range Extension

Magparangalan, Daniel P., Garrett, Timothy J., Drexler, Dieter M., Yost, Richard A.

Journal:

Analytical Chemistry

Year:

2010

Language:

english

File:

PDF, 317 KB

english, 2010

17

Cytochrome P450 2C9 is involved in flow-dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure

Fischer, Dieter, Landmesser, Ulf, Spiekermann, Stephan, Hilfiker-Kleiner, Denise, Hospely, Marian, Müller, Maja, Busse, Rudi, Fleming, Ingrid, Drexler, Helmut

Journal:

European Journal of Heart Failure

Year:

2007

Language:

english

File:

PDF, 354 KB

english, 2007

18

Automated identification of isotopically labeled pesticides and metabolites by intelligent ‘real time’ liquid chromatography tandem mass spectrometry using a bench-top ion trap mass spectrometer

Dieter M. Drexler, Philip R. Tiller, Sibylle M. Wilbert, Frederick Q. Bramble, Jae C. Schwartz

Journal:

Rapid Communications in Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 229 KB

english, 1998

19

Mechanism of coronary artery restenosis after stenting for acute myocardial infarction

Arnd Schaefer, Gunnar Klein, Dieter Fischer, Gerd Peter Meyer, Helmut Drexler, Dirk Hausmann

Journal:

The American Journal of Cardiology

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

20

A double-blind, randomized, placebo-controlled multicenter clinical trial to evaluate the effects of the angiotensin II receptor blocker candesartan cilexetil on intimal hyperplasia after coronary stent implantation

Peter W. Radke, Hans R. Figulla, Helmut Drexler, Heinrich G. Klues, Andreas Mügge, Sigmund Silber, Werner Daniel, Alexander Schmeisser, Nicolaus Reifart, Wolfgang Motz, Hans-Joachim Büttner, Dieter Fi

Journal:

American Heart Journal

Year:

2006

Language:

english

File:

PDF, 131 KB

english, 2006

21

Cytotoxic Xanthones from Psorospermum molluscum from the Madagascar Rain Forest △

Leet, John E., Liu, Xiaohong, Drexler, Dieter M., Cantone, Joseph L., Huang, Stella, Mamber, Stephen W., Fairchild, Craig R., Hussain, Raouf, Newman, David J., Kingston, David G. I.

Journal:

Journal of Natural Products

Year:

2008

Language:

english

File:

PDF, 87 KB

english, 2008

22

Stable isotope labeling by amino acids in cell culture-based liquid chromatography–mass spectrometry assay to measure microtubule dynamics in neuronal cell cultures

Polson, Craig, Cantone, Joseph L., Wei, Cong, Drexler, Dieter M., Meredith, Jere E.

Journal:

Analytical Biochemistry

Year:

2014

Language:

english

File:

PDF, 883 KB

english, 2014

23

An Automated High Throughput Liquid Chromatography–Mass Spectrometry Process to Assess the Metabolic Stability of Drug Candidates

Drexler, Dieter M., Belcastro, James V., Dickinson, Kenneth E., Edinger, Kurt J., Hnatyshyn, Serhiy Y., Josephs, Jonathan L., Langish, Robert A., McNaney, Colleen A., Santone, Kenneth S., Shipkova, Pe

Journal:

Assay and Drug Development Technologies

Year:

2007

Language:

english

File:

PDF, 14.93 MB

english, 2007

24

SPIE Proceedings [SPIE SPIE Photonics Europe - Brussels, Belgium (Monday 16 April 2012)] Biophotonics: Photonic Solutions for Better Health Care III - Towards a laser-integrated module for marker-free sorting of micrometer-sized particles in microfluidic channels

Schwarz, Wolfgang, Popp, Jürgen, Drexler, Wolfgang, Bergmann, Anna, Márquez del Pino, Antonio Jorge, Tuchin, Valery V., Matthews, Dennis L., Wahl, Dietmar, Rimpf, Dieter, Mappes, Timo, Michalzik, Rain

Year:

2012

Language:

english

File:

PDF, 2.74 MB

english, 2012

25

Synergistic inhibition of Aβ production by combinations of γ-secretase modulators

Robertson, Alan S., Iben, Lawrence G., Wei, Cong, Meredith, Jere E., Drexler, Dieter M., Banks, Martyn, Vite, Gregory D., Olson, Richard E., Thompson, Lorin A., Albright, Charles F., Ahlijanian, Micha

Journal:

European Journal of Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

26

Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp. II. Isolation, Characterization, and Structure Determination.

LEET, JOHN E., LI, WENYING, AX, HELEN A., MATSON, JAMES A., HUANG, STELLA, HUANG, RON, CANTONE, JOSEPH L., DREXLER, DIETER, DALTERIO, RICHARD A., LAM, KIN S.

Journal:

The Journal of Antibiotics

Year:

2003

Language:

english

File:

PDF, 1.25 MB

english, 2003

27

A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen

Kasia Kieltyka, Jun Zhang, Shu Li, Marianne Vath, Chris Baglieri, Cheryl Ferraro, Tatyana A. Zvyaga, Dieter M. Drexler, Harold N. Weller, Wilson Z. Shou

Journal:

Rapid Communications in Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 914 KB

english, 2009

28

Addressing the need for biomarker liquid chromatography/mass spectrometry assays: A protocol for effective method development for the bioanalysis of endogenous compounds in cerebrospinal fluid

Benitex, Yulia, McNaney, Colleen A., Luchetti, David, Schaeffer, Eric, Olah, Timothy V., Morgan, Daniel G., Drexler, Dieter M.

Journal:

Rapid Communications in Mass Spectrometry

Year:

2013

Language:

english

File:

PDF, 406 KB

english, 2013

29

Analysis of l-serine-O-phosphate in cerebrospinal spinal fluid by derivatization–liquid chromatography/mass spectrometry

McNaney, Colleen A., Benitex, Yulia, Luchetti, David, Labasi, Jeffrey M., Olah, Timothy V., Morgan, Daniel G., Drexler, Dieter M.

Journal:

Analytical Biochemistry

Year:

2014

Language:

english

File:

PDF, 327 KB

english, 2014

30

One day from dyspnea to death

Johannes Hadem, Frank Schröder, Thomas Winkler, Bernhard Gohrbandt, Dieter Fischer, Thomas Korte, Helmut Drexler

Journal:

Clinical Research in Cardiology

Year:

2006

Language:

english

File:

PDF, 235 KB

english, 2006

31

Helicobacter pylori Infection Is Associated with Higher CD4 T Cell Counts and Lower HIV-1 Viral Loads in ART-Naïve HIV-Positive Patients in Ghana

Sarfo, Fred Stephen, Eberhardt, Kirsten Alexandra, Dompreh, Albert, Kuffour, Edmund Osei, Soltau, Mareike, Schachscheider, Marei, Drexler, Jan Felix, Eis-Hübinger, Anna Maria, Häussinger, Dieter, Oten

Journal:

Year:

2015

Language:

english

File:

PDF, 462 KB

english, 2015

32

‘Intelligent’ fraction collection to improve structural characterization by mass spectrometry

Dieter M. Drexler, Philip R. Tiller

Journal:

Rapid Communications in Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 267 KB

english, 1998

33

Improving the LC-MS bioanalysis of hydrophilic peptides utilizing vacuum-based sample preparation

Wei, Cong, Cantone, Joseph L., Leet, John E., Drexler, Dieter M.

Journal:

Analytical Methods

Year:

2014

Language:

english

File:

PDF, 407 KB

english, 2014

34

Bioanalysis of endogenous bile acids by LC-MS utilizing stable isotope labeled analogues

Zheng, Joanna J., Shields, Eric E., Snow, Kimberly J., Nelson, David M., Olah, Timothy V., Reily, Michael D., Robertson, Donald G., Shipkova, Petia A., Stryker, Steven A., Xin, Baomin, Drexler, Dieter

Journal:

Analytical Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

35

Development of an on-line automated sample clean-up method and liquid chromatography–tandem mass spectrometry analysis: application in an in vitro proteolytic assay

Dieter Drexler, Deborah J. Barlow, Paul Falk, Joseph Cantone, Dennis Hernandez, Asoka Ranasinghe, Mark Sanders, Bethanne Warrack, Fiona McPhee

Journal:

Analytical and Bioanalytical Chemistry

Year:

2006

Language:

english

File:

PDF, 281 KB

english, 2006

36

Correction: Normalization strategy for the LC-MS bioanalysis of protein kinetics assays via internal proteolytic analyte utilized as control standard: application in studies of HIV-1 protease cleavage of HIV-1 Gag polyprotein in HIV maturation inhibition research

Cantone, Joseph L., Lin, Zeyu, Dicker, Ira B., Drexler, Dieter M.

Journal:

Analytical Methods

Year:

2017

Language:

english

File:

PDF, 138 KB

english, 2017

37

Strategy to Improve the Quantitative LC-MS Analysis of Molecular Ions Resistant to Gas-Phase Collision Induced Dissociation: Application to Disulfide-Rich Cyclic Peptides

Ciccimaro, Eugene, Ranasinghe, Asoka, D’Arienzo, Celia, Xu, Carrie, Onorato, Joelle, Drexler, Dieter M., Josephs, Jonathan L., Poss, Michael, Olah, Timothy

Journal:

Analytical Chemistry

Year:

2014

Language:

english

File:

PDF, 731 KB

english, 2014

38

Fluid status telemedicine alerts for heart failure: a randomized controlled trial

Böhm, Michael, Drexler, Helmut, Oswald, Hanno, Rybak, Karin, Bosch, Ralph, Butter, Christian, Klein, Gunnar, Gerritse, Bart, Monteiro, Joao, Israel, Carsten, Bimmel, Dieter, Käab, Stefan, Huegl, Burkh

Journal:

European Heart Journal

Year:

2016

Language:

english

File:

PDF, 533 KB

english, 2016

39

Bioanalysis of (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) in rat plasma using derivatization liquid chromatography/mass spectrometry

Benitex, Yulia, Luan, Fu-Ni, Shields, Eric, McNaney, Colleen A, Morgan, Daniel G, Olah, Timothy V, Drexler, Dieter M

Journal:

Year:

2014

Language:

english

File:

PDF, 869 KB

english, 2014

40

Universal ultrafast detector for short optical pulses based on graphene

Mittendorff, Martin, Kamann, Josef, Eroms, Jonathan, Weiss, Dieter, Drexler, Christoph, Ganichev, Sergey D., Kerbusch, Jochen, Erbe, Artur, Suess, Ryan J., Murphy, Thomas E., Chatterjee, Sangam, Kolat

Journal:

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

41

Utility of mass spectrometry in the mass isotopomer distribution analysis of stable isotope-labeled biomarkers in cerebrospinal fluid

Dieter Drexler, Joseph Cantone, Craig Polson, Cong Wei, Jere Meredith

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

42

Dynamic Changes of Retinal Microaneurysms in Diabetes Imaged With In Vivo Adaptive Optics Optical Coherence Tomography

Hafner, Julia, Salas, Matthias, Scholda, Christoph, Vogl, Wolf-Dieter, Drexler, Wolfgang, Schmidt-Erfurth, Ursula, Pircher, Michael, Karst, Sonja

Journal:

Investigative Opthalmology & Visual Science

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

43

865-1 Endothelium-derived hyperpolarizing factor is involved in flow-dependent dilation of peripheral conduit arteries in healthy volunteers

Fischer, Dieter, Spiekermann, Stephan, Landmesser, Ulf, Hospely, Marian, Jategaonkar, Smita, Fleming, Ingrid, Drexler, Helmut, Hornig, Burkhard

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 68 KB

english, 2004

44

A laser-driven nanosecond proton source for radiobiological studies

Bin, Jianhui, Allinger, Klaus, Assmann, Walter, Dollinger, Günther, Drexler, Guido A., Friedl, Anna A., Habs, Dieter, Hilz, Peter, Hoerlein, Rainer, Humble, Nicole, Karsch, Stefan, Khrennikov, Konsta

Journal:

Applied Physics Letters

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

45

Ionization sources and mass analyzers in MS imaging

Tsai, Yu-Hsuan, Menger, Robert F, Drexler, Dieter M, Yost, Richard A, Garrett, Timothy J

Journal:

Year:

2015

Language:

english

File:

PDF, 2.09 MB

english, 2015

46

Simultaneous bioanalysis of a phosphate prodrug and its parent compound using a multiplexed LC–MS method

Browning, Marc R, Drexler, Dieter M, Olah, Timothy V, Morgan, Daniel G

Journal:

Year:

2010

Language:

english

File:

PDF, 1.44 MB

english, 2010

47

Advances in mass spectrometry applied to pharmaceutical metabolomics

Dieter M. Drexler, Michael D. Reily, Petia A. Shipkova

Journal:

Analytical and Bioanalytical Chemistry

Year:

2011

Language:

english

File:

PDF, 389 KB

english, 2011

48

Sustained risk of recurrent thromboembolic events in patients with patent foramen ovale and paradoxical embolism: long-term follow-up over more than 15

Dieter Fischer, Ajmal Gardiwal, Jonas Haentjes, Gunnar Klein, Gerd-Peter Meyer, Helmut Drexler, Dirk Hausmann, Arnd Schaefer

Journal:

Clinical Research in Cardiology

Year:

2012

Language:

english

File:

PDF, 294 KB

english, 2012

49

Mass spectrometry techniques for qualitative and quantitative analysis of biomarkers

Dieter M. Drexler, Jean H.M. Feyen, Mark Sanders

Journal:

Drug Discovery Today: Technologies

Year:

2004

Language:

english

File:

PDF, 383 KB

english, 2004

50

Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays

Zhang, Jun, Maloney, Jennifer, Drexler, Dieter M, Cai, Xianmei, Stewart, Jeremy, Mayer, Chris, Herbst, John, Weller, Harold, Shou, Wilson Z

Journal:

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

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